Guideline-directed medical therapy across the ejection-fraction spectrum — recommendation class, dosing, mechanism, landmark trials, and bedside pearls.
Sources: 2022 AHA/ACC/HFSA Heart Failure Guideline (Circulation 2022;145:e895–e1032) · 2023 ESC HF focused update · landmark trials cited per class · FINEARTS-HF (NEJM 2024, finerenone in HFmrEF/HFpEF).
Educational reference only — not medical advice. Recommendation classes and dosing reflect published guidelines at time of release; verify against current society recommendations and your institution's protocols before applying at the bedside.