Cardiology Topic

The S3 is the finding.

The heart-failure exam by likelihood ratio: the S3 rules in, crackles and edema barely move you, and only a normal BNP rules out.

Reviewed July 2026 · verify against current guidelines

Bedside Evidence · Heart Failure

The S3 is the finding.

In the dyspneic patient, most of what we dutifully document barely moves the needle. A few findings genuinely do.

The exam

FindingLR+Read
S3 gallop11Rules in. The best exam finding.
History of heart failure5.8Moderate. Ask for it.
Jugular venous distension5.1Moderate. Trust it.
Crackles2.8Small. Weaker than taught.
Lower-extremity edema2.3Small. Weak on its own.

Beyond the exam

TestLRRead
Chest x-ray congestionLR+ 12Rules in.
BNP <100 pg/mLLR- 0.11Rules out.

Wang et al., JAMA 2005, dyspneic adults in the emergency department.

The S3 rules in. Nothing on the exam rules out. A normal BNP does.
LR+ positive likelihood ratioLR- negative likelihood ratioBNP B-type natriuretic peptide

Sources

Verify against current guidelines and local protocol before acting.

  1. Wang et al., JAMA 2005 (The Rational Clinical Examination)

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